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专利名称:Microfluidic methods发明人:Stevan B. Jovanovich,William D.
Nielsen,Michael Van Nguyen
申请号:US122665申请日:20091218公开号:US08672532B2公开日:20140318
专利附图:
摘要:This invention provides microfluidic devices that comprise a fluidics layer havingmicrofluidic channels and one or more regulating layers that regulate the movement offluid in the channels. The microfluidic devices can be used to mix one or more fluids. At
least a portion of the fluidics layer can be isolated from the regulating layer, for examplein the form of a shelf. Such isolated portions can be used as areas in which thetemperature of liquids is controlled. Also provided are instruments including thermalcontrol devices into which the microfluidic device is engaged so that the thermal controldevice controls temperature in the isolated portion, and a movable magnetic assemblyincluding magnets with shields so that a focused magnetic field can be applied to orwithdrawn from the isolated portion or any other portion of the microfluidic device. Alsoprovided are methods of mixing fluids. The methods include stacking a plurality ofalternating boluses of different liquids in a microfluidic channel, and moving the stackedboluses through the channel. In another method, the boluses are moved into adiaphragm valve having a volume able to accommodate several boluses, and thenpumping the liquids out of the valve.
申请人:Stevan B. Jovanovich,William D. Nielsen,Michael Van Nguyen
地址:Livermore CA US,San Jose CA US,San Diego CA US
国籍:US,US,US
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