专利内容由知识产权出版社提供
专利名称：5-O-DESOSAMINYLERYTHRONOLIDE A
DERIVATIVE
发明人：ASAKA, Toshifumi, Taisho Pharmaceutical Co.
Ltd.,KASHIMURA, Masato, TaishoPharmaceutical Co. Ltd.,MISAWA, Yoko,Taisho Pharmaceutical Co. Ltd.,MORIMOTO,Shigeo, Taisho Pharmaceutical Co.Ltd.,HATAYAMA, Katsuo, TaishoPharmaceutical Co. Ltd.
申请号：EP93909404.1申请日：19930421公开号：EP0638585A1公开日：19950215
摘要：Object: to provide a novel macrolide antibiotic having a potent antibacterialactivity. Constitution: a tricyclic carbamate derivative of a 3-oxo-6-methoxy-substituted 5-O-desosaminylerythronolide A derivative represented by general fomula (I), and apharmaceutically acceptable acid addition salt thereof. In formula (I), -A represents -N(R³)- (wherein R³ represents hydrogen or C₁-C₃ alkyl) or -N=; and R¹ and R² representeach C₁-C₃ alkyl. An intermediate, represented by general formula (II), useful forproducing the 3-oxo-substituted 5-O-desosaminylerythronolide A derivative, wherein R⁴represents acetyl or propionyl.
申请人：TAISHO PHARMACEUTICAL CO. LTD
地址：24-1 Takata 3-chome Toshima-ku Tokyo 171 JP
国籍：JP
代理机构：Kraus, Walter, Dr.
更多信息请下载全文后查看
